Cefuroxime axetil to treat gonorrhea.

نویسندگان

  • R P Das
  • K Jones
  • A J Robinson
  • D J Timmins
چکیده

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منابع مشابه

Comparative clinical efficacy of single oral doses of cefuroxime axetil and amoxicillin in uncomplicated gonococcal infections.

Cefuroxime axetil (1.5 g) was compared with amoxicillin (3 g), both given as a single oral dose combined with probenecid (1 g) for the treatment of uncomplicated gonorrhea. Of 60 evaluable patients receiving amoxicillin, 55 (91.7%) were cured, whereas 55 (96.5%) of the 57 patients receiving cefuroxime axetil were cured (P greater than 0.1). Both drugs were well tolerated.

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Comparison of single-dose cefuroxime axetil with ciprofloxacin in treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase-producing Neisseria gonorrhoeae strains.

A randomized, multicenter, investigator-blind trial was conducted to compare the efficacies of cefuroxime axetil and ciprofloxacin for treatment of patients with uncomplicated gonorrhea caused by penicillinase-producing Neisseria gonorrhoeae (PPNG). A total of 832 patients (434 females and 398 males) received a single oral dose of cefuroxime axetil (1,000 mg [417 patients]) or ciprofloxacin (50...

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Clinical comparison of single-oral-dose cefuroxime axetil and amoxicillin with probenecid for uncomplicated gonococcal infections in women.

Four hundred sixty-six female patients were enrolled in a randomized study that compared the clinical efficacies of single oral doses of cefuroxime axetil and amoxicillin with probenecid in the treatment of uncomplicated gonorrhea. Two hundred ninety-five patients had culture-positive gonococcal infections and completed the investigation. Cure rates for the patients treated with cefuroxime axet...

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Oral cefuroxime axetil compared with oral ampicillin in treating acute uncomplicated gonorrhoea.

The efficacy and tolerance of single oral doses of cefuroxime axetil (1.5 g) were compared with oral ampicillin (3 g) for treating acute gonococcal urethritis in 110 men and 30 women. Each dose was given with 1 g probenecid. Of the 62 assessable patients who received ampicillin, two failed to respond to treatment. Of 67 assessable patients who received cefuroxime axetil, one failed to respond. ...

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Cefuroxime Axetil (Ceftin®): A Brief Review

KEY WORDS cefuroxime axetil; antimicrobial; uncomplicated gonorrhea efuroxime axetil (Ceftin(R), Glaxo Wellcome, Research Triangle Park, NC) is the oral pro-drug formulation of the injectable antibiotic cefu-roxime sodium. It has essentially the same antibac-terial activity as its parent moiety, making cefurox-ime the only second-generation cephalosporin with both an intravenous and oral formul...

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عنوان ژورنال:
  • Genitourinary medicine

دوره 64 6  شماره 

صفحات  -

تاریخ انتشار 1988